杨俊杰

杨俊杰，教授，理学博士，硕士生导师。主要从事与医养健康、精准诊疗相关的生物医学、微生物与免疫学、特医食品、生物绿色环保面料新材料、工艺等领域的研究。

主要学习、工作经历

山东师范大学，发育生物学专业，博士。

2019年，参加教育部出国留学人员培训部英语高级培训，成绩合格。

2020年，荣获山东省政府公派留学人员（教育系统）录取资助。

2023-2024年，山东省公派高级访问学者。在新加坡国立大学National University of Singapore, Yong Loo Lin School of Medicine，Department of Microbiology & Immunology 访学一年。

2023-至今 临沂大学《生物医学工程领域》硕士专业学位研究生指导导师。

主要科研成果

1）荣获2023年度中国商业联合会科学技术奖-全国商业科技进步奖 “三等奖”。

2）主持山东省技术开发横向课题《生物绿色环保纺织面料新材料、新工艺、新产品相关的技术研发》一 项；

主持山东省技术开发横向课题2023HX0114《生物绿色环保纺织面料新材料、新工艺、新产品相关的技术研发》一项；

主持山东省工业和信息化厅202150100443《特应性皮炎(AD)菌群精准评估及皮肤微生态个性化干预体系》1项；

主持威海市科技企业孵化器发展计划项目《海洋医用食品制备技术研究》1项；

主持山东省自然科学基金项目2015ZRB01226《口腔菌群结构动态变化与胃 癌发生发展相关性的研究》1项；

参与山东省重点研发计划项目2016YYSP009《以海洋生物资源为原料的高附加值医用食品制备及检测关键技术研究》1项；

参与山东省重大科技创新工程项目2018CXGC1219《性早熟儿童肠道菌群精准评估及肠道微生态个性化干预体系》1项。

3）授权国家发明专利3项《肠道及口腔菌群多样性及差异性的分析方法》、《植物提取物及其制备方法》 、《脑术后失眠患者脑活监测系统》

授权国家新型实用专利5项《唾液采集设备》、《口腔样本采集设备》、《一种粪便试样采集装置》、《一种血培养仪孵育模块摇摆监测装置》、《一种血培养仪很恒温孵育装置》，

授权计算机软件著作权《HC-BC120血培养仪协处理器控制软件》1项。

  4）出版学术专著《欢迎走进微生物组》1部。

  5）发表SCI学术论文21篇。

    代表性论文发表在mSystems, （Q1）, Pharmacological Research, (Q1), Genomics，Proteomics & Bioinformatics，(Q1)，Frontiers in Microbiology， (Q1), Frontiers in Oncology， (Q2)，Microbiome, (Q1）等。

1) Changying Zhao^#, Zefeng Wei^#, Junjie Yang^#, Jiaming Zhang, Chunna Yu, Aijun Yang, Min Zhang, Lin Zhang, Ye Wang, Xiaofeng Mu, Xueyuan Heng, Huijun Yang, Zhongtao Gai, Xuenan Wang, Lei Zhang^*. Characterization of vaginal microbiome in women with infertility and its potential correlation with hormone stimulation during IVF surgery. mSystems, 2020, 5(4): e00450-20.

2）Ying Wang^#, Ning Li^#, Jun-Jie Yang ^#, Dong-Mei Zhao, Bin Chen5, Guo-Qing Zhang, Shuo Chen, Rui-Fang Cao, Han Yu, Chang-Ying Zhao, Lu Zhao, Yong-Sheng Ge, Yi Liu,  Le-Hai Zhang, Wei Hu, Lei Zhang^*, Zhong-Tao Gai^*.Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder. Pharmacological Research, 2020, 157:104784.

3) Junjie Yang^#, Jiaming Zhang^#, Changying Zhao^#, Zhongtao Gai, Xiaofeng Mu, Ye Wang, Chunling Zhang, Zhenzhen Su, Lihe Gao, Dequan Zhu, Zhiwen Zuo, Xueyuan Heng^*, Lei Zhang^*. Blood loss leads to increase in relative abundance of opportunistic pathogens in the gut microbiome of rabbits. Current Microbiology, 2020, 77: 415-424.

4）Li Ning^#, Junjie Yang^#, Jiaming Zhang, Cheng Liang, Ying Wang, Bin Chen, Changying Zhao, Jingwen Wang, Guangye Zhang, Dongmei Zhao, Yi Liu, Lehai Zhang, Jun Yang, Guimei Li^*, Zhongtao Gai^*, Lei Zhang^*, Guoping Zhao. Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment. Genomics, Proteomics & Bioinformatics, 2019, 17(1):26-28.

5）Zhen Zhang^#, Junjie Yang^#, Qiang Feng, Bin Chen3, Meihui Li,Cheng Liang, Mingyu Li, Zhihui Li, Qin Xu, Lei Zhang^*, Wantao Chen^*.Compositional and Functional Analysis of the Microbiome in Tissue and Saliva of Oral Squamous Cell Carcinoma. Frontiers in Microbiology, 2019, 10: 1439.

6) Fanghua Zhang^#, Meng Wang^#, Junjie Yang^#, Qian Xu, Cheng Liang, Bin Chen, Jiaming Zhang, Ying Yang, Huiling Wang, Yongfang Shang, Ye Wang, Xiaofeng Mu, Dequan Zhu, Chunling Zhang, Minxiu Yao^*, Lei Zhang^*. Response of gut microbiota in type 2 diabetes to hypoglycemic agents. Endocrine, 2019, 66(3):485-493.

7) Meng Wang^#, Junjie Yang^#, Zhongtao Gai, Shengnan Huo, Jianhua Zhu, Jun Li, Ranran Wang, Sheng Xing, Guosheng Shi, Feng Shi^*, Lei Zhang^*. Comparison between digital PCR and real-time PCR in detection of Salmonella typhimurium in milk. International Journal of Food Microbiology, 2018, 266: 251-256.

8）XueYing Zhang^#, Gansukh Sukhchuluun^#, TingBei Bo^#, QingSheng Chi, JunJie Yang, Bin Chen, Lei Zhang^*, DeHua Wang^*, Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure, Microbiome, 2018, 6: 103.

9）Junjie Yang^#, Xiaofeng Mu, Ye Wang, Dequan Zhu, Jiaming Zhang, Cheng Liang, Bin Chen, Jingwen Wang, Changying Zhao, Zhiwen Zuo, Xueyuan Heng^*, Chunling Zhang^*, Lei Zhang^*. Dysbiosis of the salivary microbiome is associated with non-smoking female lung cancer and correlated with immunocytochemistry markers. Frontiers in Oncology, 2018, 8: 520.

10）Shen Meng^#, Bin Chen^#, Junjie Yang^#, Jingwen Wang, Dequan Zhu, Qingsong Meng^*, Lei Zhang^*. Study of Microbiomes in Aseptically Collected Samples of Human Breast Tissue Using Needle Biopsy and the Potential Role of in situ Tissue Microbiomes for Promoting Malignancy. Frontiers in Oncology, 2018, 8:318.